MEDICAL FIELD: Laboratory: Anticoagulants
LOCATION: Aarhus C, Denmark

Anticoagulants (ACs) are administered to more than 2% of the population in the western world for prevention of blood clots. When AC patients are in need of urgent care (e.g. suffering from a stroke or major bleed) it is of utmost importance to determine the level of AC to facilitate correct clinical management including guiding AC reversal and surgery. In such events, point-of-care (POC) tests using blood clotting is often employed. Patients are shifting towards a new drug class for AC treatment (Direct Oral Anticoagulants (DOACs)), for which there is no POC test. The only method available is a centralized, time consuming and complex method at specialized hospitals. Rapid and correct clinical management is crucial to improve patient outcome and reduce hospital resources, but clinicians lack a tool to rapidly guide management at all hospitals. There is, therefore, a need for a POC DOAC tests. POC determination of drug levels is important in numerous other cases including drug monitoring


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